International Journal of Immunology

Volume 4, Issue 1, February 2016

  • Fas Mediated(CD95L) Periferal T-cell Apotosis Marker in Monitoring HIV-1 Disease Progression in Adults in Yaoundé, Cameroon

    George Mondinde Ikomey, Atashili Julius, Graeme Brendon Jacobs, Martha Tongo Mesembe, Agnes Eyoh, Emilia Lyonga, Okomo Assoumou Marie Claire

    Issue: Volume 4, Issue 1, February 2016
    Pages: 1-5
    Received: 21 November 2015
    Accepted: 29 November 2015
    Published: 22 March 2016
    Abstract: sFas (CD95) / FasL are hallmarks of apoptosis involvement in pathogenesis of HIV. We assess changes in soluble Fas /FasL, CD4 % and HIV-1 viral load in patients prior to the initiation of antiretroviral therapy (ART) and 6 months thereafter. A prospective longitudinal study on sixty consented HIV-1 positive adults. sFas and sFasL levels were measur... Show More