Background: HIV a major challenge to the whole world since the last quarter of 20th century but has become a member of a manageable chronic disease since the advent of ARV drugs. The non-adherence to Antiretroviral Therapy is an emerging major challenge to AIDS care. Objective: To assess factors associated with adherence among AIDS patients receiving Antiretroviral Therapy at Wolaita Soddo Hospital, Southern Ethiopia. Method: A cross sectional study was carried out at Wolaita Soddo Hospital from April 15 to May 15, 2012 E.C. The collected data were entered in Epi Info version3.5.3. Data analyses were done using SPSS for windows version 16.0. Descriptive analysis was used to describe the data. Binary logistic regression analysis was used to measure the association between the dependent variable and independent variables calculating odds ratio and its 95% confidence interval (CI). Statistical significance was set at α. ≤ 0.05. Multivariable analyses were applied to identify the relative effect of explanatory variables on the dependent variable. Results: Three hundred and fifty seven HIV/ AIDS patients were involved in the study. Multi-method adherence assessment consisting of self-report, monthly dispense schedule and dietary requirements ,were used to measure adherence and the average adherence rate was 74.4%.Multivariate logistic regression analysis showed that, with whom a subject lives (AOR=4.943,1,(2.168-11.270)), depression(AOR=2.221,1,(1.093-4.515)), and having inadequate diet to take with ART (AOR=2.229,1,(1.034-4.807)), were independent predictors of dose adherence. Conclusions: In conclusion living with a partner, having no depression and having no food scarcity to take with ART have association with adherence to ART regimens.
| Published in | Science Journal of Public Health (Volume 2, Issue 2) |
| DOI | 10.11648/j.sjph.20140202.15 |
| Page(s) | 69-77 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2014. Published by Science Publishing Group |
Antiretroviral Treatment, Adherence, HIV/AIDS, Ethiopia
| [1] | Annual Performance Report of HSDP-III, Ministry of Health, Federal Democratic Republic of Ethiopia, EFY2001, (2008/2009) |
| [2] | Health and Health Related Indicators, Federal Ministry of Health, Planning and Programming Department: 2007/8 |
| [3] | AIDS Epidemic Update. UNAIDS, World Health Organization. Geneva. WHO 2003 |
| [4] | Samuel Sendagala ,Factors affecting the adherence to antiretroviral therapy by hiv positive patients treated in a community based hiv/aids care programme in rural Uganda A case of tororo district ,University Of South Africa ,November 2010 |
| [5] | Adherence to HIV Treatment. Geneva, Switzerland. World Health Organization 2004 |
| [6] | Bonolo, Palmira de Fae, Casar, Cibele C b, Acurio, Fransisco A ac, et al. Non-adherence among patients initiating antiretroviral therapy: a challenge for health professionals in Brazil. JAIDS. 2006; 19 Sppl4: S5-S13. |
| [7] | Nachega J. B, Stein D M, Lahnan D.A, et al. Adherence to Antiretroviral Therapy in HIVInfected Adults in Soweto, South Africa, AIDS Research and Human Retroviruses. 2004;20(10):1053-1056. |
| [8] | Adriana A, Paola TM, Rita M et al. Correlates and predictors of adherence to Highly Active Antiretroviral Therapy. JAIDS 2002;31 supplement 3:s123-s127. |
| [9] | Eliud Wekesa. ART adherence in resource poor settings in sub-Saharan Africa: a multidisciplinary review |
| [10] | HIV / AIDS IN ETHIOPIA -AN EPIDEMIOLOGICAL SYNTHESIS.Ethiopia HIV/AIDS Prevention & Control Office (HAPCO) and Global HIV/AIDS Monitoring and Evaluation Team (GAMET) april 2008.available at: www.worldbank/aids > publications |
| [11] | Nyambura Anthony Wanjohi. Factors That Influence Non–Adherence To Antiretroviral Therapy Among Hiv And Aids Patients In Central Province, Kenya April 2009. |
| [12] | Alemayehu Amberbir, Kifle Woldemichael, Sofonias Getachew, Belaineh Girma,and Kebede Deribe . Predictors of adherence to antiretroviral therapy among HIV-infected persons: a prospective study in Southwest Ethiopia,july 2008 |
| [13] | Yared Mekonnen, Eduard Sanders, Tsehaynesh Messele, Dawit Wolday,Wendelien Dorigo-Zestma, Ab Schaap, Walelgne Mekonnen, Hailu Meless1,Wude Mihret, Arnaud Fontanet, Roel A. Coutinho and Nicole H.T.M. Dukers, Prevalence and Incidence of, and Risk Factors for,HIV-1 Infection among Factory Workers in Ethiopia, 1997-2001 |
| [14] | Chesney, MA. 2000. Factors affecting adherence to antiretroviral therapy. Clinical Infectious Diseases 30(2):171-176. |
| [15] | Arnsten, JH, Demas,PA, Farzadegan, H, Grant, RW, Gourevitch, MN, Chang, CJ, Buono, D, Eckholdt, H, Howard, AA, & Schoenbaun, EE .2001. Antiretroviral therapy adherence and viral suppression in HIV-infected drug users: comparison of self-report and electronic monitoring. Clinical Infectious Diseases 33:1417-1423. |
| [16] | Tadios Y, Davey G. Retroviral drug adherence & its correlates in Addis Ababa, Ethiopia; Ethiop Med J 2006; 44:237-244. |
| [17] | Chishimba S and Zulu F. The 3x5 HIV and AIDS Treatment Plan; Challenges for Developing Countries from Zambian Perspective. Int Conf AIDS. (2004). 15: Abstract no. B11132 |
| [18] | Orrell C, Bangsberg DR, Badri M, Wood R. Adherence is not a barrier to successful antiretroviral therapy in South Africa. AIDS. 2003;17:1369–75. doi: 10.1097/00002030-200306130-00011. |
| [19] | Sarna A., Luchter S., Giebel S., Munyau P., Kaai S., Shikely K., Mandaliya K., Hawken M., Van Dam J., and Temmerman M. "Promoting adherence to antiretroviral therapy through a directly administered antiretroviral therapy (DAART) strategy in Mombassa Kenya, Horizons Research Update. Nairobi: Population Council. 2005. |
| [20] | Poppa, A., Davidson, D., Deutsch, J., "British HIV Association (BHIVA)/British Association for sexual health and HIV (N‘BASHH) guidelines on provision of adherence support to individuals receiving antiretroviral therapy" HIVMedicine 2004 ,5:S 46-60. |
| [21] | Ekanem Esu Williams,A Study on Social Support and ART Adherence at Carletonville Hospital and Zola Clinic in Gauteng Province.South Africa,2007 |
| [22] | Michaels, D, Darder, M; Boulle A; et al; Adherence to antiretroviral treatment: the Experience of patients on ART for longer than 24 months. Oral presentation, 2nd South Africa AIDS Conference Durban, June 2005. |
APA Style
Amsalu Alagaw, Wanzahun Godana, Mohammed Taha, Tariku Dejene. (2014). Factors associated with Antiretroviral Treatment Adherence among Adult Patients in Wolaita Soddo Hospital, Wolaita Zone, Southern Ethiopia. Science Journal of Public Health, 2(2), 69-77. https://doi.org/10.11648/j.sjph.20140202.15
ACS Style
Amsalu Alagaw; Wanzahun Godana; Mohammed Taha; Tariku Dejene. Factors associated with Antiretroviral Treatment Adherence among Adult Patients in Wolaita Soddo Hospital, Wolaita Zone, Southern Ethiopia. Sci. J. Public Health 2014, 2(2), 69-77. doi: 10.11648/j.sjph.20140202.15
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Download@article{10.11648/j.sjph.20140202.15,
author = {Amsalu Alagaw and Wanzahun Godana and Mohammed Taha and Tariku Dejene},
title = {Factors associated with Antiretroviral Treatment Adherence among Adult Patients in Wolaita Soddo Hospital, Wolaita Zone, Southern Ethiopia},
journal = {Science Journal of Public Health},
volume = {2},
number = {2},
pages = {69-77},
doi = {10.11648/j.sjph.20140202.15},
url = {https://doi.org/10.11648/j.sjph.20140202.15},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20140202.15},
abstract = {Background: HIV a major challenge to the whole world since the last quarter of 20th century but has become a member of a manageable chronic disease since the advent of ARV drugs. The non-adherence to Antiretroviral Therapy is an emerging major challenge to AIDS care. Objective: To assess factors associated with adherence among AIDS patients receiving Antiretroviral Therapy at Wolaita Soddo Hospital, Southern Ethiopia. Method: A cross sectional study was carried out at Wolaita Soddo Hospital from April 15 to May 15, 2012 E.C. The collected data were entered in Epi Info version3.5.3. Data analyses were done using SPSS for windows version 16.0. Descriptive analysis was used to describe the data. Binary logistic regression analysis was used to measure the association between the dependent variable and independent variables calculating odds ratio and its 95% confidence interval (CI). Statistical significance was set at α. ≤ 0.05. Multivariable analyses were applied to identify the relative effect of explanatory variables on the dependent variable. Results: Three hundred and fifty seven HIV/ AIDS patients were involved in the study. Multi-method adherence assessment consisting of self-report, monthly dispense schedule and dietary requirements ,were used to measure adherence and the average adherence rate was 74.4%.Multivariate logistic regression analysis showed that, with whom a subject lives (AOR=4.943,1,(2.168-11.270)), depression(AOR=2.221,1,(1.093-4.515)), and having inadequate diet to take with ART (AOR=2.229,1,(1.034-4.807)), were independent predictors of dose adherence. Conclusions: In conclusion living with a partner, having no depression and having no food scarcity to take with ART have association with adherence to ART regimens.},
year = {2014}
}
TY - JOUR T1 - Factors associated with Antiretroviral Treatment Adherence among Adult Patients in Wolaita Soddo Hospital, Wolaita Zone, Southern Ethiopia AU - Amsalu Alagaw AU - Wanzahun Godana AU - Mohammed Taha AU - Tariku Dejene Y1 - 2014/02/28 PY - 2014 N1 - https://doi.org/10.11648/j.sjph.20140202.15 DO - 10.11648/j.sjph.20140202.15 T2 - Science Journal of Public Health JF - Science Journal of Public Health JO - Science Journal of Public Health SP - 69 EP - 77 PB - Science Publishing Group SN - 2328-7950 UR - https://doi.org/10.11648/j.sjph.20140202.15 AB - Background: HIV a major challenge to the whole world since the last quarter of 20th century but has become a member of a manageable chronic disease since the advent of ARV drugs. The non-adherence to Antiretroviral Therapy is an emerging major challenge to AIDS care. Objective: To assess factors associated with adherence among AIDS patients receiving Antiretroviral Therapy at Wolaita Soddo Hospital, Southern Ethiopia. Method: A cross sectional study was carried out at Wolaita Soddo Hospital from April 15 to May 15, 2012 E.C. The collected data were entered in Epi Info version3.5.3. Data analyses were done using SPSS for windows version 16.0. Descriptive analysis was used to describe the data. Binary logistic regression analysis was used to measure the association between the dependent variable and independent variables calculating odds ratio and its 95% confidence interval (CI). Statistical significance was set at α. ≤ 0.05. Multivariable analyses were applied to identify the relative effect of explanatory variables on the dependent variable. Results: Three hundred and fifty seven HIV/ AIDS patients were involved in the study. Multi-method adherence assessment consisting of self-report, monthly dispense schedule and dietary requirements ,were used to measure adherence and the average adherence rate was 74.4%.Multivariate logistic regression analysis showed that, with whom a subject lives (AOR=4.943,1,(2.168-11.270)), depression(AOR=2.221,1,(1.093-4.515)), and having inadequate diet to take with ART (AOR=2.229,1,(1.034-4.807)), were independent predictors of dose adherence. Conclusions: In conclusion living with a partner, having no depression and having no food scarcity to take with ART have association with adherence to ART regimens. VL - 2 IS - 2 ER -
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