Factors Associated with the Progression of Preeclampsia at Kinshasa University Clinics in Democratic Republic of Congo

Vangu Vangu Roland; Rahma Rashid Tozin; Mbuyi Muamba Jean Marie; Mokondjimobe Etienne; Mambueni Thamba Christophe; Vangu Ngoma Dieudonné; Tsimba Vangu Andrien; Makoso Nimi Blaise; Mbungu Fuele Simon; Nkodila Natuhoyila Aliocha; Longo-Mbenza Benjamin

doi:doi:10.11648/j.ejpm.20200805.12

Factors Associated with the Progression of Preeclampsia at Kinshasa University Clinics in Democratic Republic of Congo

Vangu Vangu Roland, Rahma Rashid Tozin, Mbuyi Muamba Jean Marie, Mokondjimobe Etienne, Mambueni Thamba Christophe, Vangu Ngoma Dieudonné, Tsimba Vangu Andrien, Makoso Nimi Blaise, Mbungu Fuele Simon, Nkodila Natuhoyila Aliocha, Longo-Mbenza Benjamin

Published in European Journal of Preventive Medicine (Volume 8, Issue 5)

Received: 6 August 2020 Accepted: 24 August 2020 Published: 25 September 2020

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Abstract

Background and aims: the progression of preeclampsia continues to increase in sub-Saharan Africa where care is inadequate. The objective of this study is to identify factors associated with the progression of preeclampsia at University Clinics of Kinshasa. Methods: This is a prospective and analytical study of 265 patients hospitalized at the Gynecology Service of the University Clinics of Kinshasa between January 1, 2006 and December 31, 2015. The clinical, biological, therapeutic and evolutionary characteristics were the parameters of 'interest. Cox regression in multivariate analyzes was generated to identify risk factors for progression to the p <0.05 threshold. Results: The cumulative frequency of preeclapse decreased from 6.0% in the first year to 64.2% at the end of the study with periods of stagnation in the rate. Predictors of the progression of preeclampsia in the study population for F values equal to 2.86, 2.10, 3.57, 3.23, 2.81 and 0.005 and an α risk equal at 0.009; 0.014; 0.006; 0.007; 0.005 and 0.006 0.0005, respectively, for age, level of education, occupation, SAP, DBP and figure 3, led us to reject the null hypothesis of equality of means between progression and the lack of progression. In multiple cox regression, the risk of progression of preeclampsia was 3 times respectively in parturients aged > 35 years (aRR: 2.57 95% CI: 1.89-4.75), in female employees (aRR: 2.83 95% CI: 1.97-4.46); this risk was 2 times respectively among academics, PAS and PAD elevated. Treatment under scheme 3, on the other hand, reduced the risk of progression 2 (aRR: 0.43 95% CI: 0.28-0.63). Conclusion: the progression of pre-eclampsia could be linked to certain socio-demographic and clinical factors. The role played by the treatment regimen of αmethyl Dopa + Nifedipine + Diazepam remains to be defined in this subgroup.

Published in	European Journal of Preventive Medicine (Volume 8, Issue 5)
DOI	10.11648/j.ejpm.20200805.12
Page(s)	66-71
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Progression, Preeclampsia, Risk Factors, CUK

References

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APA Style

Vangu Vangu Roland, Rahma Rashid Tozin, Mbuyi Muamba Jean Marie, Mokondjimobe Etienne, Mambueni Thamba Christophe, et al. (2020). Factors Associated with the Progression of Preeclampsia at Kinshasa University Clinics in Democratic Republic of Congo. European Journal of Preventive Medicine, 8(5), 66-71. https://doi.org/10.11648/j.ejpm.20200805.12

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ACS Style

Vangu Vangu Roland; Rahma Rashid Tozin; Mbuyi Muamba Jean Marie; Mokondjimobe Etienne; Mambueni Thamba Christophe, et al. Factors Associated with the Progression of Preeclampsia at Kinshasa University Clinics in Democratic Republic of Congo. Eur. J. Prev. Med. 2020, 8(5), 66-71. doi: 10.11648/j.ejpm.20200805.12

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AMA Style

Vangu Vangu Roland, Rahma Rashid Tozin, Mbuyi Muamba Jean Marie, Mokondjimobe Etienne, Mambueni Thamba Christophe, et al. Factors Associated with the Progression of Preeclampsia at Kinshasa University Clinics in Democratic Republic of Congo. Eur J Prev Med. 2020;8(5):66-71. doi: 10.11648/j.ejpm.20200805.12

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@article{10.11648/j.ejpm.20200805.12,
  author = {Vangu Vangu Roland and Rahma Rashid Tozin and Mbuyi Muamba Jean Marie and Mokondjimobe Etienne and Mambueni Thamba Christophe and Vangu Ngoma Dieudonné and Tsimba Vangu Andrien and Makoso Nimi Blaise and Mbungu Fuele Simon and Nkodila Natuhoyila Aliocha and Longo-Mbenza Benjamin},
  title = {Factors Associated with the Progression of Preeclampsia at Kinshasa University Clinics in Democratic Republic of Congo},
  journal = {European Journal of Preventive Medicine},
  volume = {8},
  number = {5},
  pages = {66-71},
  doi = {10.11648/j.ejpm.20200805.12},
  url = {https://doi.org/10.11648/j.ejpm.20200805.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejpm.20200805.12},
  abstract = {Background and aims: the progression of preeclampsia continues to increase in sub-Saharan Africa where care is inadequate. The objective of this study is to identify factors associated with the progression of preeclampsia at University Clinics of Kinshasa. Methods: This is a prospective and analytical study of 265 patients hospitalized at the Gynecology Service of the University Clinics of Kinshasa between January 1, 2006 and December 31, 2015. The clinical, biological, therapeutic and evolutionary characteristics were the parameters of 'interest. Cox regression in multivariate analyzes was generated to identify risk factors for progression to the p  35 years (aRR: 2.57 95% CI: 1.89-4.75), in female employees (aRR: 2.83 95% CI: 1.97-4.46); this risk was 2 times respectively among academics, PAS and PAD elevated. Treatment under scheme 3, on the other hand, reduced the risk of progression 2 (aRR: 0.43 95% CI: 0.28-0.63). Conclusion: the progression of pre-eclampsia could be linked to certain socio-demographic and clinical factors. The role played by the treatment regimen of αmethyl Dopa + Nifedipine + Diazepam remains to be defined in this subgroup.},
 year = {2020}
}

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TY  - JOUR
T1  - Factors Associated with the Progression of Preeclampsia at Kinshasa University Clinics in Democratic Republic of Congo
AU  - Vangu Vangu Roland
AU  - Rahma Rashid Tozin
AU  - Mbuyi Muamba Jean Marie
AU  - Mokondjimobe Etienne
AU  - Mambueni Thamba Christophe
AU  - Vangu Ngoma Dieudonné
AU  - Tsimba Vangu Andrien
AU  - Makoso Nimi Blaise
AU  - Mbungu Fuele Simon
AU  - Nkodila Natuhoyila Aliocha
AU  - Longo-Mbenza Benjamin
Y1  - 2020/09/25
PY  - 2020
N1  - https://doi.org/10.11648/j.ejpm.20200805.12
DO  - 10.11648/j.ejpm.20200805.12
T2  - European Journal of Preventive Medicine
JF  - European Journal of Preventive Medicine
JO  - European Journal of Preventive Medicine
SP  - 66
EP  - 71
PB  - Science Publishing Group
SN  - 2330-8230
UR  - https://doi.org/10.11648/j.ejpm.20200805.12
AB  - Background and aims: the progression of preeclampsia continues to increase in sub-Saharan Africa where care is inadequate. The objective of this study is to identify factors associated with the progression of preeclampsia at University Clinics of Kinshasa. Methods: This is a prospective and analytical study of 265 patients hospitalized at the Gynecology Service of the University Clinics of Kinshasa between January 1, 2006 and December 31, 2015. The clinical, biological, therapeutic and evolutionary characteristics were the parameters of 'interest. Cox regression in multivariate analyzes was generated to identify risk factors for progression to the p  35 years (aRR: 2.57 95% CI: 1.89-4.75), in female employees (aRR: 2.83 95% CI: 1.97-4.46); this risk was 2 times respectively among academics, PAS and PAD elevated. Treatment under scheme 3, on the other hand, reduced the risk of progression 2 (aRR: 0.43 95% CI: 0.28-0.63). Conclusion: the progression of pre-eclampsia could be linked to certain socio-demographic and clinical factors. The role played by the treatment regimen of αmethyl Dopa + Nifedipine + Diazepam remains to be defined in this subgroup.
VL  - 8
IS  - 5
ER  -

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Author Information

Vangu Vangu Roland

Départment of Gynécology and Obstétric, University of Kinshasa, Kinshasa, Democratic Republic of Congo
Rahma Rashid Tozin

Départment of Gynécology and Obstétric, University of Kinshasa, Kinshasa, Democratic Republic of Congo
Mbuyi Muamba Jean Marie

Départment of Gynécology and Obstétric, University of Kinshasa, Kinshasa, Democratic Republic of Congo
Mokondjimobe Etienne

Department of Public Health, Lomo-University Reseach, Kinshasa, Democratic Republic of Congo
Mambueni Thamba Christophe

Department of Public Health, Lomo-University Reseach, Kinshasa, Democratic Republic of Congo
Vangu Ngoma Dieudonné

Department of Public Health, Lomo-University Reseach, Kinshasa, Democratic Republic of Congo
Tsimba Vangu Andrien

Department of Internal Medecine, University of Président Joseph KASA-VUBU, Boma, Democratic Republic of Congo
Makoso Nimi Blaise

Department of Internal Medecine, University of Président Joseph KASA-VUBU, Boma, Democratic Republic of Congo
Mbungu Fuele Simon

Department of Public Health, Lomo-University Reseach, Kinshasa, Democratic Republic of Congo
Nkodila Natuhoyila Aliocha

Department of Public Health, Lomo-University Reseach, Kinshasa, Democratic Republic of Congo
Longo-Mbenza Benjamin

Départment of Gynécology and Obstétric, University of Kinshasa, Kinshasa, Democratic Republic of Congo

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APA Style

Vangu Vangu Roland, Rahma Rashid Tozin, Mbuyi Muamba Jean Marie, Mokondjimobe Etienne, Mambueni Thamba Christophe, et al. (2020). Factors Associated with the Progression of Preeclampsia at Kinshasa University Clinics in Democratic Republic of Congo. European Journal of Preventive Medicine, 8(5), 66-71. https://doi.org/10.11648/j.ejpm.20200805.12

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ACS Style

Vangu Vangu Roland; Rahma Rashid Tozin; Mbuyi Muamba Jean Marie; Mokondjimobe Etienne; Mambueni Thamba Christophe, et al. Factors Associated with the Progression of Preeclampsia at Kinshasa University Clinics in Democratic Republic of Congo. Eur. J. Prev. Med. 2020, 8(5), 66-71. doi: 10.11648/j.ejpm.20200805.12

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AMA Style

Vangu Vangu Roland, Rahma Rashid Tozin, Mbuyi Muamba Jean Marie, Mokondjimobe Etienne, Mambueni Thamba Christophe, et al. Factors Associated with the Progression of Preeclampsia at Kinshasa University Clinics in Democratic Republic of Congo. Eur J Prev Med. 2020;8(5):66-71. doi: 10.11648/j.ejpm.20200805.12

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@article{10.11648/j.ejpm.20200805.12,
  author = {Vangu Vangu Roland and Rahma Rashid Tozin and Mbuyi Muamba Jean Marie and Mokondjimobe Etienne and Mambueni Thamba Christophe and Vangu Ngoma Dieudonné and Tsimba Vangu Andrien and Makoso Nimi Blaise and Mbungu Fuele Simon and Nkodila Natuhoyila Aliocha and Longo-Mbenza Benjamin},
  title = {Factors Associated with the Progression of Preeclampsia at Kinshasa University Clinics in Democratic Republic of Congo},
  journal = {European Journal of Preventive Medicine},
  volume = {8},
  number = {5},
  pages = {66-71},
  doi = {10.11648/j.ejpm.20200805.12},
  url = {https://doi.org/10.11648/j.ejpm.20200805.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejpm.20200805.12},
  abstract = {Background and aims: the progression of preeclampsia continues to increase in sub-Saharan Africa where care is inadequate. The objective of this study is to identify factors associated with the progression of preeclampsia at University Clinics of Kinshasa. Methods: This is a prospective and analytical study of 265 patients hospitalized at the Gynecology Service of the University Clinics of Kinshasa between January 1, 2006 and December 31, 2015. The clinical, biological, therapeutic and evolutionary characteristics were the parameters of 'interest. Cox regression in multivariate analyzes was generated to identify risk factors for progression to the p  35 years (aRR: 2.57 95% CI: 1.89-4.75), in female employees (aRR: 2.83 95% CI: 1.97-4.46); this risk was 2 times respectively among academics, PAS and PAD elevated. Treatment under scheme 3, on the other hand, reduced the risk of progression 2 (aRR: 0.43 95% CI: 0.28-0.63). Conclusion: the progression of pre-eclampsia could be linked to certain socio-demographic and clinical factors. The role played by the treatment regimen of αmethyl Dopa + Nifedipine + Diazepam remains to be defined in this subgroup.},
 year = {2020}
}

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TY  - JOUR
T1  - Factors Associated with the Progression of Preeclampsia at Kinshasa University Clinics in Democratic Republic of Congo
AU  - Vangu Vangu Roland
AU  - Rahma Rashid Tozin
AU  - Mbuyi Muamba Jean Marie
AU  - Mokondjimobe Etienne
AU  - Mambueni Thamba Christophe
AU  - Vangu Ngoma Dieudonné
AU  - Tsimba Vangu Andrien
AU  - Makoso Nimi Blaise
AU  - Mbungu Fuele Simon
AU  - Nkodila Natuhoyila Aliocha
AU  - Longo-Mbenza Benjamin
Y1  - 2020/09/25
PY  - 2020
N1  - https://doi.org/10.11648/j.ejpm.20200805.12
DO  - 10.11648/j.ejpm.20200805.12
T2  - European Journal of Preventive Medicine
JF  - European Journal of Preventive Medicine
JO  - European Journal of Preventive Medicine
SP  - 66
EP  - 71
PB  - Science Publishing Group
SN  - 2330-8230
UR  - https://doi.org/10.11648/j.ejpm.20200805.12
AB  - Background and aims: the progression of preeclampsia continues to increase in sub-Saharan Africa where care is inadequate. The objective of this study is to identify factors associated with the progression of preeclampsia at University Clinics of Kinshasa. Methods: This is a prospective and analytical study of 265 patients hospitalized at the Gynecology Service of the University Clinics of Kinshasa between January 1, 2006 and December 31, 2015. The clinical, biological, therapeutic and evolutionary characteristics were the parameters of 'interest. Cox regression in multivariate analyzes was generated to identify risk factors for progression to the p  35 years (aRR: 2.57 95% CI: 1.89-4.75), in female employees (aRR: 2.83 95% CI: 1.97-4.46); this risk was 2 times respectively among academics, PAS and PAD elevated. Treatment under scheme 3, on the other hand, reduced the risk of progression 2 (aRR: 0.43 95% CI: 0.28-0.63). Conclusion: the progression of pre-eclampsia could be linked to certain socio-demographic and clinical factors. The role played by the treatment regimen of αmethyl Dopa + Nifedipine + Diazepam remains to be defined in this subgroup.
VL  - 8
IS  - 5
ER  -

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