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Venous Thromboembolic Diseases: Risk and Etiological Factors in the Internal Medicine Department of the Sylvanus Olympio University Hospital in Lomé

Received: 6 January 2021     Accepted: 18 January 2021     Published: 25 January 2021
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Abstract

Introduction: Venous thromboembolic disease is a common condition. Many risk factors can contribute to its occurrence. The aim of this study is to describe the risk factors of venous thromboembolic diseases and the results of the etiological assessment. Methodology: This was a retrospective and descriptive study that took place in the internal medicine department of the Sylvanus Olympio University in Lomé, from January 1, 2016 to December 31, 2017. It included all patients of both sexes aged 18 and over hospitalized for deep vein thrombosis regardless of the site and / or documented pulmonary embolism. Results: We had collected 51 cases of venous thromboembolic disease. The mean age of the patients was 52.9 ± 17.1 years with a male predominance (52.9%). Deep venous thrombosis (DVT) of the lower limbs was the most frequent location (68.5%). In our study, 59.3% of patients presented at least one risk factor before any etiological assessment. No risk factor was found in nine patients (17.8%). The main risk factors encountered were: obesity (17.6%), HIV infection (13.7%), diabetes (11.8%), neoplasias (7.8%), and prolonged bed rest (7.8%). An etiology was found in 13.7% of cases, including 3 cases of thrombophilia and 4 cases of neoplasia. Conclusion: Obesity and HIV infection are the most common risk factors for venous thromboembolic diseases. Neoplasias are the most common etiologies after etiological investigation.

Published in Clinical Medicine Research (Volume 10, Issue 1)
DOI 10.11648/j.cmr.20211001.13
Page(s) 16-19
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Venous Thromboembolic Disease, Risk Factors, Etiologies, Lomé

References
[1] Nordström M, Lindblad B, Bergqvist D, Kjellström T. A prospective study of the incidence of deep-vein thrombosis within a denned urban population. J Intern Med. 1992; 232 (2): 155-160.
[2] Anderson FA, Wheeler HB, Goldberg RJ et al. A population based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism: The Worcester DVT study. Arch Intern Med. 1991; 151 (5): 933-938.
[3] Ferrari E, Jambou D, Fischer F, Appert-Flory A, Bayle J, M. Baudouy M. Venous thromboembolic disease in pregnant women. Sang Thrombose Vaisseaux. 1999; 11 (1): 16–21.
[4] Assi E. Contribution to the study of deep vein thrombosis in black Africans. Medicine Thesis. 2001, Abidjan.
[5] Diallo B A, Diall IB, Diakité S, Diakité M, Keita L, Ndirahisha E et al. Socio-epidemiological and evolutionary aspects of phlebitis of the lower limbs in Bamako. Afr. Ann. Thorac. Cardiovasc. Surg 2008; 3 (2): 66-69.
[6] Diall IB, Coulibaly S, Menta I, Ba Ho, Diakite M, Sidibe N et al Clinic and evolution of pulmonary embolism in 30 cases. Mali Medical. 2011; 26 (1): 3-6.
[7] Pio M, Baragou S, Afassinou Y, Atta S, Hachimou A, Ehlan K et al News on venous thromboembolic disease at the Sylvanus Olympio University Hospital in Lomé. J Rech Scien Univ Lome. 2013; 15 (1): 93-100.
[8] Denakpo J. L, Zoumenou E, Kerekou A, Dossou F, Hounton N, Sambieni O et al Prevalence and characteristics of venous thromboembolic disease in women in a hospital setting in Cotonou. Med Afr Noire. 2012; 59 (3): 163-171.
[9] Baili L, Aydi Z, Dridi M, Ben Dhaou B, Boussema F, Rokbani L. Venous thrombosis in young subjects: about 105 cases. Rev Med Interne. 2013; 34 (1): 185- 186.
[10] Sangare I, Menta I, Ba HO, Fofana CA, Sidibe N, Sogodogo A. Thrombophlebitis of members in the Cardiology department of CHU Gabriel Toure.. Mali Med. 2015; 30 (1): 3-6.
[11] Zabsonre P, Nebie LVA, Soumandoulougou A, Samandoulougou A, Toguyeni JY, Kabore JP. CO 23 Venous thromboembolic disease in Ouagadougou: role of HIV infection. Ann Dermatol Venereol 2007; 134 (1): 40.
[12] Boulieu D, Ninet J, Pinede L, Didier-Laurent JF, Franco A. Early venous thrombosis of unusual site, in early pregnancy after ovarian hyperstimulation. Contracept Fertil Sex. 1989; 17 (1): 725-727.
[13] Spencer FA, Gore JM, Lessard D, Emery C, Pacifico L, Reed G. Venous thromboembolism in the elderly. A community-based perspective. Thromb Haemost. 2008; 100 (5): 780–788.
[14] Anderson FA, Wheeler HB. Venous thromboembolism. Risk factors and prophylaxis. Clin Chest Med. 1995; 16 (2): 235-251.
[15] Niakara A, Drabo YJ, Kambire Y, Nebie VA, Kabore NJP, Simon F. Cardiovascular attacks and HIV infection: study of 79 cases at the CHN in Ouagadougou (Burkina Faso). Bull Soc Pathol Exot. 2002; 95 (1): 23-26.
[16] Saber A, Aboolian A, Laraja R, Baron H, Hanna K. HIV/AIDS and the risk of deep vein thrombosis: a study of 45 patients with lower extremity involvement. Am Surg. 2001; 67 (7): 645-647.
[17] Pottier P, Hardouin JB, Lejeune S, Jolliet P, Gillet B, Planchon B. Immobilization and the risk of venous thromboembolism. A meta-analysis on epidemiological studies. Thromb Res. 2009; 124 (4): 468-476.
[18] Haslett C, Chilvers ER, Boon NA, Colledge NR, Hunter JAA. Internal medicine principles and practices. 2nd edition 2004. Davidson. Ed Maloine.
[19] Prandoni P. Prevention and treatment of venous thromboembolism with low molecular weight heparins: clinical implications of the recent European guidelines. Thrombosis journal. 2008; 6 (13): 1-5.
[20] Houenassi DM, Bigot A, Tchabi Y, VehounkpeSacca J, Akindes-DosssoYovo R, Gbaguidi L et al. Study of protein C deficiency in venous thromboembolic disease at the CNHU in Cotonou: study carried out in 54 black African patients living in Cotonou. Ann Cardiol Angeiol. 2013; 62 (1): 8-11.
[21] Diallo BA, Yena S, Diall IB, Diakite S, Sanogo K, Keita L et al. Phlebitis of the lower limbs in a Malian university hospital environment Afr. Ann. Thorac. Cardiovasc. Surg. 2008; 3 (2): 66-69.
[22] Konin C, Adoh M, Adoubib A, Anzouan-Kacou JB, Azagoh R, N’guetta R et al. Unusual venous thrombosis indicative of human immunodeficiency virus infection and protein S deficiency. About two cases and review of the literature. Rev Med Interne. 2008; 29 (6): 508-511.
[23] Diedhiou D, Sarr A, Ndour-Mbaye N. M, Ka-Cisse M, Diop SN. Phlebitis of the lower limbs in internal medicine. Epidemiological, clinical and etiological aspects. About 40 cases in Dakar. Med. Afr. Noire. 2012; 59 (3): 172-176.
[24] Sevestre MA, Labarere J, Brin S, Carpentier P, Constant J, Degeilh M et al. Optimising histoty taking for evaluating the risk of venous thromboembolism: the OPTIMEV study. Journal des maladies vasculaires. 2005; 30 (4): 217-227.
[25] Meyer G. Venous thromboembolism and cancer. Rev Pneumol Clin. 2014; 70 (1-2): 91-94.
Cite This Article
  • APA Style

    Edem Komi Mossi, Abdou Razak Moukaila, Dzidzonu Komi Nemi, Waina Kodjo, Sodjehoun Apeti, et al. (2021). Venous Thromboembolic Diseases: Risk and Etiological Factors in the Internal Medicine Department of the Sylvanus Olympio University Hospital in Lomé. Clinical Medicine Research, 10(1), 16-19. https://doi.org/10.11648/j.cmr.20211001.13

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    ACS Style

    Edem Komi Mossi; Abdou Razak Moukaila; Dzidzonu Komi Nemi; Waina Kodjo; Sodjehoun Apeti, et al. Venous Thromboembolic Diseases: Risk and Etiological Factors in the Internal Medicine Department of the Sylvanus Olympio University Hospital in Lomé. Clin. Med. Res. 2021, 10(1), 16-19. doi: 10.11648/j.cmr.20211001.13

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    AMA Style

    Edem Komi Mossi, Abdou Razak Moukaila, Dzidzonu Komi Nemi, Waina Kodjo, Sodjehoun Apeti, et al. Venous Thromboembolic Diseases: Risk and Etiological Factors in the Internal Medicine Department of the Sylvanus Olympio University Hospital in Lomé. Clin Med Res. 2021;10(1):16-19. doi: 10.11648/j.cmr.20211001.13

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  • @article{10.11648/j.cmr.20211001.13,
      author = {Edem Komi Mossi and Abdou Razak Moukaila and Dzidzonu Komi Nemi and Waina Kodjo and Sodjehoun Apeti and Agbeko Kodjo Djagadou and Abago Balaka and Awalou l Mohaman Djibri},
      title = {Venous Thromboembolic Diseases: Risk and Etiological Factors in the Internal Medicine Department of the Sylvanus Olympio University Hospital in Lomé},
      journal = {Clinical Medicine Research},
      volume = {10},
      number = {1},
      pages = {16-19},
      doi = {10.11648/j.cmr.20211001.13},
      url = {https://doi.org/10.11648/j.cmr.20211001.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20211001.13},
      abstract = {Introduction: Venous thromboembolic disease is a common condition. Many risk factors can contribute to its occurrence. The aim of this study is to describe the risk factors of venous thromboembolic diseases and the results of the etiological assessment. Methodology: This was a retrospective and descriptive study that took place in the internal medicine department of the Sylvanus Olympio University in Lomé, from January 1, 2016 to December 31, 2017. It included all patients of both sexes aged 18 and over hospitalized for deep vein thrombosis regardless of the site and / or documented pulmonary embolism. Results: We had collected 51 cases of venous thromboembolic disease. The mean age of the patients was 52.9 ± 17.1 years with a male predominance (52.9%). Deep venous thrombosis (DVT) of the lower limbs was the most frequent location (68.5%). In our study, 59.3% of patients presented at least one risk factor before any etiological assessment. No risk factor was found in nine patients (17.8%). The main risk factors encountered were: obesity (17.6%), HIV infection (13.7%), diabetes (11.8%), neoplasias (7.8%), and prolonged bed rest (7.8%). An etiology was found in 13.7% of cases, including 3 cases of thrombophilia and 4 cases of neoplasia. Conclusion: Obesity and HIV infection are the most common risk factors for venous thromboembolic diseases. Neoplasias are the most common etiologies after etiological investigation.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Venous Thromboembolic Diseases: Risk and Etiological Factors in the Internal Medicine Department of the Sylvanus Olympio University Hospital in Lomé
    AU  - Edem Komi Mossi
    AU  - Abdou Razak Moukaila
    AU  - Dzidzonu Komi Nemi
    AU  - Waina Kodjo
    AU  - Sodjehoun Apeti
    AU  - Agbeko Kodjo Djagadou
    AU  - Abago Balaka
    AU  - Awalou l Mohaman Djibri
    Y1  - 2021/01/25
    PY  - 2021
    N1  - https://doi.org/10.11648/j.cmr.20211001.13
    DO  - 10.11648/j.cmr.20211001.13
    T2  - Clinical Medicine Research
    JF  - Clinical Medicine Research
    JO  - Clinical Medicine Research
    SP  - 16
    EP  - 19
    PB  - Science Publishing Group
    SN  - 2326-9057
    UR  - https://doi.org/10.11648/j.cmr.20211001.13
    AB  - Introduction: Venous thromboembolic disease is a common condition. Many risk factors can contribute to its occurrence. The aim of this study is to describe the risk factors of venous thromboembolic diseases and the results of the etiological assessment. Methodology: This was a retrospective and descriptive study that took place in the internal medicine department of the Sylvanus Olympio University in Lomé, from January 1, 2016 to December 31, 2017. It included all patients of both sexes aged 18 and over hospitalized for deep vein thrombosis regardless of the site and / or documented pulmonary embolism. Results: We had collected 51 cases of venous thromboembolic disease. The mean age of the patients was 52.9 ± 17.1 years with a male predominance (52.9%). Deep venous thrombosis (DVT) of the lower limbs was the most frequent location (68.5%). In our study, 59.3% of patients presented at least one risk factor before any etiological assessment. No risk factor was found in nine patients (17.8%). The main risk factors encountered were: obesity (17.6%), HIV infection (13.7%), diabetes (11.8%), neoplasias (7.8%), and prolonged bed rest (7.8%). An etiology was found in 13.7% of cases, including 3 cases of thrombophilia and 4 cases of neoplasia. Conclusion: Obesity and HIV infection are the most common risk factors for venous thromboembolic diseases. Neoplasias are the most common etiologies after etiological investigation.
    VL  - 10
    IS  - 1
    ER  - 

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Author Information
  • Department of Internal Medicine, University Hospital Sylvanus Olympio of Lome, University of Lome, Lome, Togo

  • Department of Internal Medicine, University Hospital Sylvanus Olympio of Lome, University of Lome, Lome, Togo

  • Department of Internal Medicine, University Hospital Sylvanus Olympio of Lome, University of Lome, Lome, Togo

  • Department of Internal Medicine, University Hospital Sylvanus Olympio of Lome, University of Lome, Lome, Togo

  • Department of Internal Medicine, University Hospital Sylvanus Olympio of Lome, University of Lome, Lome, Togo

  • Department of Internal Medicine, University Hospital Sylvanus Olympio of Lome, University of Lome, Lome, Togo

  • Department of Internal Medicine, University Hospital Sylvanus Olympio of Lome, University of Lome, Lome, Togo

  • Department of Internal Medicine, University Hospital Sylvanus Olympio of Lome, University of Lome, Lome, Togo

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