A study of neonatal malaria infection was conducted between 1st April 2021 to 30th October 2021 to determine the prevalence of neonatal malaria among infant admitted in Chukwuemeka Odumegwu Ojukwu University Teaching Hospital (COOHT) Amaku Awka Anambra State South Eastern Nigeria. Four Hundred and Twenty (420) neonates admitted at the General Outpatient Department (GOPD) of the Paediatrics unit. Two hundred 200 (47%) of the population were randomly selected and enrolled for the study after informed consent was sort and obtained from their mothers before enrolling them in the study The mean age of the subject is Mean (±SD) 6.86±8.51 days. One hundred and eight 108 (54%) of the subject were male and 92 (46%) female. Neonate less than 7days were 125 (62%); neonate 7-14 days of age were 50 (25%) and 14-28 days were 25 (12.5%) respectively. Thick and thin blood films were prepared from the blood specimens obtained for the neonate persevered in Ethylene Diamine Tetracetic Acid (EDTA) on a microscopic slide stained with Giemsa solution and screened for malaria parasite under a microscope following the golden rule observing all the necessary precaution in the procedure. Grading parasitemia was done using Standard measure. The result showed an overall prevalence of malaria among neonates was 74 (37.0%), and 53 (26.5%) of the Plasmodium were negative while 73 (36.5%) of the screening test was not accessed (attrition). Recommendations were made and conclusion drawn.
| Published in | American Journal of Life Sciences (Volume 11, Issue 1) |
| DOI | 10.11648/j.ajls.20231101.12 |
| Page(s) | 6-10 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2023. Published by Science Publishing Group |
Malaria, Congenital, Neonatal, Prevalence
| [1] | Global Partnership for a Malaria Free World (GPFMFW) World Malaria Report; 2012. |
| [2] | Malaria NO MORE United Kingdom, (MNMUK). Nigeria has More Cases and Deaths from Malaria than Any Other Country in the World. Available from: http://www.malarianomore.org.uk/our-work/protecting/Nigeria. (Last accessed on 2016 April 28). |
| [3] | Lagos State Ministry of Health (LSMOH) Malaria Control Program accessed on 2016 May 07. |
| [4] | UNICEF 2016 April 28. Malaria Still Number Killer of Children Under Five in Nigeria. Available from: http://www.unicef.org/Nigeria e from: hssttp://www.lagosstateministryofhealth.com. |
| [5] | Olupot-Olupot, P., Eregu I. E., Naizuli, K, Ikiror. J, Acom L., Burgoine, K (2018) Neonatal and Congenital Malaria: A Case Series in Malaria Endemic Eastern Uganda Malaria J. 20; 17 (1): 171. |
| [6] | Arvin A. M., Maldonado, Y. A., (1995) Protozoan and Helminth Infections. In: Remington, J. S., Klein, J. O., editors. Infectious Diseases of the Fetus and Newborn Infant. 4th ed. WB Saunders; Philadelphia: pp. 765–768. |
| [7] | Krause P. J., (2004) Malaria (Plasmodium) In: Behrman, R. E., Keligman, R., Jenson H. B., editors. Nelson Textbook of Pediatrics. 17th ed. W. B Saunders; Philadelphia. pp. 1139–1143. |
| [8] | Subramanian D., Moise, K. J., White, A. C (1992) Imported malaria in pregnancy: Report of four cases and review of management. Clin Infect Dis. 15: 408. |
| [9] | Ibhanesebhor, S. E (1995). Clinical characteristics of Neonatal Malaria. Journal of Tropical Pediatrics, 41, 330-333. |
| [10] | Mukhtar, M., (2007). The growing incidence of neonatal malaria–a situational review in developing countries. Niger J Med. 16: 25–30. |
| [11] | Ekanem, A. D., Anah, M. U., Udo, J. J., (2008). The prevalence of congenital malaria among neonates with suspected sepsis in Calabar, Nigeria. Trop Doct. 38: 73–6. |
| [12] | Okafor, U. H., Oguonu, T., Onah, H. E., (2006). Risk factors associated with congenital malaria in Enugu, South Eastern Nigeria. J Obstet Gynaecol 26: 612-6. |
| [13] | Snow, R. W., Guerra, C. A., Noor, A. M., Myint, H. Y., Hay, S. I., (2005). The Global distribution of clinical episodes of Plasmodium falciparum malaria. Nature 434: 214-2. |
| [14] | Osungbade, K. O., Oladunjoye, O. O., (2012). Prevention of congenital transmission of malaria in sub-Saharan African countries: challenges and implications for health system strengthening. J Trop Med. 2012: 648456. |
| [15] | Riley, E. M., Wagner, G. E., Akanmori, B. D., Koram, K. A., (2001). Do maternally acquired antibodies protect infants from malaria infection? Parasite Immunol. 23: 51–59. |
| [16] | Mabunda, S., Aponte, J. J., Tiago, A and Alonso, P ((2009). A country-wide malaria survey in Mozambique. II. Malaria attributable proportion of fever and establishment of malaria case definition in children across different epidemiological settings. Malar J 8: 74. |
| [17] | Falade, C., Mokuolu, O., Okafor, H., Orogade, A., Falade, A., Adedoyin, O., Oguonu, T., Maman, A., Hamer, D. H., Callahan, M. V., (2007). Epidemiology of congenital malaria in Nigeria: a multi-centre study. Trop Med Int Health. 12: 1279–1287. |
| [18] | Hyacinth, H. I., Oguche, S., Yilgwan, C. S., (2012). Summary description of 24 cases of neonatal malaria seen at a tertiary health center in Nigeria. Iran J Pediatr. 22: 87–91. |
| [19] | Runsewe-Abiodun, I. T., Ogunfowora, O. B., and Fetuga, B. M., (2006) Neonatal malaria in Nigeria -a 2-year review. BMC Pediatrics 6: 19. |
| [20] | Gosling, R. D., Okell, L., Mosha, J. D., Chandramohan, D., (2011). The role of antimalarial treatment in the elimination of malaria Clinical Microbiology and Infection 17 (11): 1617-23. |
| [21] | Aponte, JJ., Schellenberg, D., Egan, A., Breckenridge, A., Carneiro, I., Critchley, J., Ina Danquah, I., Dodoo, A., Kobbe, R., Lell, B., May, J., Premji, Z., Sanz, S., Sevene, E., Soulaymani-Becheikh, R., Winstanley, P., Adjei, S., Anemana, S., Chandramohan, D., Issifou, S., Mockenhaupt, F., Owusu-Agyei S., Greenwood, B., Grobusch, MP., Kremsner, P. G., Macete, E., Mshinda, H., Newman, RD., Slutsker, L., Tanner, M., Alonso, P., Menendez, C (2009) Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo-controlled trials. Lancet 31; 374 (9700): 1533-1542. |
| [22] | Le Hesran J. Y., (2000). The particularities of malaria in the child. Med Trop. 60: 92–98. |
| [23] | World Health Organisation, “World Malaria Report,” WHO, Geneva, Switzerland, pp. 99-101, 2008. |
APA Style
Okonkwo Victor Okechukwu, Nwankwo Ifeoma Cordelia, Ikeh Ifeanyi Mulumba. (2023). Neonatal Malaria Prevalence Among Infant Aged 1-28 Days Adamitted in Chukwuemeka Odumaegwu Ojukwu University Teaching Hospital Amaku Awka. American Journal of Life Sciences, 11(1), 6-10. https://doi.org/10.11648/j.ajls.20231101.12
ACS Style
Okonkwo Victor Okechukwu; Nwankwo Ifeoma Cordelia; Ikeh Ifeanyi Mulumba. Neonatal Malaria Prevalence Among Infant Aged 1-28 Days Adamitted in Chukwuemeka Odumaegwu Ojukwu University Teaching Hospital Amaku Awka. Am. J. Life Sci. 2023, 11(1), 6-10. doi: 10.11648/j.ajls.20231101.12
AMA Style
Okonkwo Victor Okechukwu, Nwankwo Ifeoma Cordelia, Ikeh Ifeanyi Mulumba. Neonatal Malaria Prevalence Among Infant Aged 1-28 Days Adamitted in Chukwuemeka Odumaegwu Ojukwu University Teaching Hospital Amaku Awka. Am J Life Sci. 2023;11(1):6-10. doi: 10.11648/j.ajls.20231101.12
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.ajls.20231101.12,
author = {Okonkwo Victor Okechukwu and Nwankwo Ifeoma Cordelia and Ikeh Ifeanyi Mulumba},
title = {Neonatal Malaria Prevalence Among Infant Aged 1-28 Days Adamitted in Chukwuemeka Odumaegwu Ojukwu University Teaching Hospital Amaku Awka},
journal = {American Journal of Life Sciences},
volume = {11},
number = {1},
pages = {6-10},
doi = {10.11648/j.ajls.20231101.12},
url = {https://doi.org/10.11648/j.ajls.20231101.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.20231101.12},
abstract = {A study of neonatal malaria infection was conducted between 1st April 2021 to 30th October 2021 to determine the prevalence of neonatal malaria among infant admitted in Chukwuemeka Odumegwu Ojukwu University Teaching Hospital (COOHT) Amaku Awka Anambra State South Eastern Nigeria. Four Hundred and Twenty (420) neonates admitted at the General Outpatient Department (GOPD) of the Paediatrics unit. Two hundred 200 (47%) of the population were randomly selected and enrolled for the study after informed consent was sort and obtained from their mothers before enrolling them in the study The mean age of the subject is Mean (±SD) 6.86±8.51 days. One hundred and eight 108 (54%) of the subject were male and 92 (46%) female. Neonate less than 7days were 125 (62%); neonate 7-14 days of age were 50 (25%) and 14-28 days were 25 (12.5%) respectively. Thick and thin blood films were prepared from the blood specimens obtained for the neonate persevered in Ethylene Diamine Tetracetic Acid (EDTA) on a microscopic slide stained with Giemsa solution and screened for malaria parasite under a microscope following the golden rule observing all the necessary precaution in the procedure. Grading parasitemia was done using Standard measure. The result showed an overall prevalence of malaria among neonates was 74 (37.0%), and 53 (26.5%) of the Plasmodium were negative while 73 (36.5%) of the screening test was not accessed (attrition). Recommendations were made and conclusion drawn.},
year = {2023}
}
TY - JOUR T1 - Neonatal Malaria Prevalence Among Infant Aged 1-28 Days Adamitted in Chukwuemeka Odumaegwu Ojukwu University Teaching Hospital Amaku Awka AU - Okonkwo Victor Okechukwu AU - Nwankwo Ifeoma Cordelia AU - Ikeh Ifeanyi Mulumba Y1 - 2023/04/18 PY - 2023 N1 - https://doi.org/10.11648/j.ajls.20231101.12 DO - 10.11648/j.ajls.20231101.12 T2 - American Journal of Life Sciences JF - American Journal of Life Sciences JO - American Journal of Life Sciences SP - 6 EP - 10 PB - Science Publishing Group SN - 2328-5737 UR - https://doi.org/10.11648/j.ajls.20231101.12 AB - A study of neonatal malaria infection was conducted between 1st April 2021 to 30th October 2021 to determine the prevalence of neonatal malaria among infant admitted in Chukwuemeka Odumegwu Ojukwu University Teaching Hospital (COOHT) Amaku Awka Anambra State South Eastern Nigeria. Four Hundred and Twenty (420) neonates admitted at the General Outpatient Department (GOPD) of the Paediatrics unit. Two hundred 200 (47%) of the population were randomly selected and enrolled for the study after informed consent was sort and obtained from their mothers before enrolling them in the study The mean age of the subject is Mean (±SD) 6.86±8.51 days. One hundred and eight 108 (54%) of the subject were male and 92 (46%) female. Neonate less than 7days were 125 (62%); neonate 7-14 days of age were 50 (25%) and 14-28 days were 25 (12.5%) respectively. Thick and thin blood films were prepared from the blood specimens obtained for the neonate persevered in Ethylene Diamine Tetracetic Acid (EDTA) on a microscopic slide stained with Giemsa solution and screened for malaria parasite under a microscope following the golden rule observing all the necessary precaution in the procedure. Grading parasitemia was done using Standard measure. The result showed an overall prevalence of malaria among neonates was 74 (37.0%), and 53 (26.5%) of the Plasmodium were negative while 73 (36.5%) of the screening test was not accessed (attrition). Recommendations were made and conclusion drawn. VL - 11 IS - 1 ER -
Email: